Jonesboro is located at 35°50'31" North, 90°42'15" West (35.842222, -90.704167).
According to the United States Census Bureau, the city has a total area of 80.00 mi2 (207.19 km2). 79.64 mi2 (206.25 km2) of it is land and 0.36 mi2 (0.94 km2) of it is covered by water. The total area is 0.45% water.
Jonesboro is located in the Central Standard Time (CST) timezone, GMT-06:00. It observes Daylight Saving Time (DST).