Brisbane is located at 37°40'50" North, 122°23'54" West (37.680556, -122.398611).
According to the United States Census Bureau, the city has a total area of 20.53 mi2 (53.17 km2). 3.32 mi2 (8.60 km2) of it is land and 17.21 mi2 (44.57 km2) of it is covered by water. The total area is 83.83% water.
Brisbane is located in the Pacific Standard Time (PST) timezone, GMT-08:00. It observes Daylight Saving Time (DST).