Las Cruces is located at 32°18'42" North, 106°46'40" West (32.311944, -106.777778).
According to the United States Census Bureau, the city has a total area of 52.22 mi2 (135.25 km2). 52.09 mi2 (134.92 km2) of it is land and 0.13 mi2 (0.33 km2) of it is covered by water. The total area is 0.25% water.
Las Cruces is located in the Mountain Standard Time (MST) timezone, GMT-07:00. It observes Daylight Saving Time (DST).