League City is located at 29°30'25" North, 95°5'39" West (29.507222, -95.094444).
According to the United States Census Bureau, the city has a total area of 52.35 mi2 (135.59 km2). 51.24 mi2 (132.71 km2) of it is land and 1.11 mi2 (2.88 km2) of it is covered by water. The total area is 2.13% water.
League City is located in the Central Standard Time (CST) timezone, GMT-06:00. It observes Daylight Saving Time (DST).