Blacksburg is located at 37°13'45" North, 80°24'51" West (37.229167, -80.414167).
According to the United States Census Bureau, the town has a total area of 19.37 mi2 (50.18 km2). 19.36 mi2 (50.14 km2) of it is land and 0.02 mi2 (0.04 km2) of it is covered by water. The total area is 0.08% water.
Blacksburg is located in the Eastern Standard Time (EST) timezone, GMT-05:00. It observes Daylight Saving Time (DST).