Danville is located at 36°35'8" North, 79°23'43" West (36.585833, -79.395278).
According to the United States Census Bureau, the city has a total area of 43.94 mi2 (113.80 km2). 43.06 mi2 (111.53 km2) of it is land and 0.88 mi2 (2.27 km2) of it is covered by water. The total area is 1.99% water.
Danville is located in the Eastern Standard Time (EST) timezone, GMT-05:00. It observes Daylight Saving Time (DST).